Technical Papers and Presentations

Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Effect of Electrical Field Distortion on Particle-Particle Interaction Under DEP

G. Zhang[1], Y. Zhao[1], J. Hodge[1], J. Brcka[2], J. Faguet[2], E. Lee[2]
[1]Clemson University, Clemson, SC, USA
[2]TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

In using DEP for particle manipulation, researchers often use a formula to calculate the DEP forces in which the forces are proportional to the particle radius to the third power. This formula assumes that the electrical field, E, will not be affected by the presence of a particle, no matter what the actual size and the dielectric property of the particle are. This work confirms that the ...

A Comparison Between an A-V and V Formulation in Transcranial Magnetic Stimulation

B. Granula[1], K. Porzig[2], H. Toepfer[2], M. Gacanovic[1]
[1]University of Banja Luka, Banja Luka, Bosnia-Herzegovina
[2]Technische Universität Ilmenau, Ilmenau, Germany

The prediction of the exact location and intensity of the electric field induced in the human brain during Transcranial magnetic stimulation is a nontrivial computational task. Numerical simulations of the procedure can be used to acquire first approximations in a safe and controlled environment. In order to make this approach more accessible, it is necessary to reduce computation time as much as ...

Improving Detection Sensitivity for Nanoscale Targets Through Combined Photonic and Plasmonic Techniques

G. Zhang[1], Y. Zhao[1]
[1]Clemson University, Clemson, SC, USA

Photonic technique such as the whispering gallery mode (WGM) is often used for detection of small particles like bacteria and viruses. It offers good detection sensitivity and is advantageous over other detection techniques because the detection can be label free. However, the detection sensitivity may not be sufficient when the size of the detection target is in nanoscale. To change this, we use ...

Simulating Organogenesis in COMSOL Multiphysics®: Parameter Optimization for PDE-based Models

D. Iber[1], D. Menshykau[2], P. Germann[2], L. Lermuzeaux[2,3]
[1]D-BSSE, ETH Zurich, Switzerland, SIB, Basel, Switzerland
[2]D-BSSE, ETH Zurich, Basel, Switzerland
[3]Department of Bioengineering, University of Nice-Sophia Antipolis, Nice, France

Morphogenesis is a tightly regulated process that has been studied for decades. Previously we developed data-based mechanistic models for a range of developmental processes with a view to integrate the available knowledge and to better understand the underlying regulatory logic. In our previous papers on simulating organogenesis in COMSOL Multiphysics® we discussed methods to efficiently solve ...

Application of the Focused Impedance Method (FIM) to Determine the Volume of an Object within a Volume Conductor

M. A. Kadir[1], S. P. Ahmed[2], G. D. Al Quaderi[3], R. Rahman[2], K. Siddique-e Rabbani[1]
[1]Department of Biomedical Physics & Technology, University of Dhaka, Dhaka, Bangladesh
[2]Department of Physics, Jahangirnagar University, Savar, Dhaka, Bangladesh
[3]Department of Physics, University of Dhaka, Dhaka, Bangladesh

Focused Impedance Method (FIM), a new technique of electrical impedance measurement having high sensitivity in the central region, can sense the change in transfer impedance of an object embedded at a shallow depth within a volume conductor of unchanging background conductivity, using electrodes at the surface. This paper presents a new method for measuring the volume of such an embedded object ...

Simulation of Chemotractant Gradients in Microfluidic Channels to Study Cell Migration Mechanism in Silico

P. Wallin[1], E. Bernson[1], J. Gold[1]
[1]Chalmers University of Technology, Applied Physics, Biological Physics, Gothenburg, Sweden

Cell migration of endothelial cells along gradients is an important process in vivo and an interesting target for cancer therapeutics. Microfluidics offer very powerful tools to study such migration processes in detail in the lab. In this study, we describe a model to simulate molecular gradients in a diffusion based microfluidic gradient generator and how a cell senses these gradients via cell ...

Computational Analysis on Commercially Available Stent Designs

K. Basu[1], P. Ghosh[2], S. Bhattacharjee[2], S. Das [2], A. Chanda[1]
[1]School of Bio Science and Engineering, Jadavpur University, Kolkata, West Bengal, India
[2]Department of Mechanical Engineering, Jadavpur University, Kolkata, West Bengal, India

Cardiovascular disease has become a major healthcare problem. To tackle this along with bypass surgery, the use of the cardiovascular stent is considered promising and effective. In this study, we aim to find the effectiveness of stent deployments and their influence on haemodynamics post their deployment in human arteries. For the study we have reconstructed single units of two commercially ...

Simulation Organogenesis in COMSOL: Deforming and Interacting Domains

D. Iber[1], D. Menshykau[1]
[1]D-BSSE, ETH Zurich, Basel, Switzerland

Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to better understand the underlying regulatory logic. Organ size changes dramatically during development, and tissues are composed of several layers that may expand ...

COMSOL Thermal Model for a Heated Neural Micro-Probe

M. Christian[1], S. Firebaugh[1], A. Smith[1]
[1]United States Naval Academy, Annapolis, MD, USA

This project utilizes the heat transfer module of the COMSOL Multiphysics environment to model the effects that an ohmic heating probe will have on neural tissue. The model quantifies the thermal impact of active components embedded on a neural micro probe by solving the Penne’s bioheat equation with an external MATLAB function to determine the heat generation along the length of the probe. ...

Some Commonly Neglected Issues Which Affect DEP Applications

G. Zhang[1], V. Pandian[1], J. Brcka[2], J. Faguet[2], E. Lee[2]
[1]Clemson University, Clemson, SC, USA
[2]TEL U.S. Holdings, Inc., U.S. Technology Development Center, Austin, TX, USA

Dielectrophoresis (or DEP) has been exploited for various micro and nano fluidics applications like patterning, sorting and separation. However, there are several commonly neglected issues in quantifying DEP forces. Such negligence could potentially lead to wrong DEP force predictions and estimates, posing difficulties in correlating experimental observations with theories. Among the commonly ...

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