Showing result: 1 - 10 of 12
Biotechnology
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3D Fluid-Structure Interaction Simulation of an Obstacle in a Fluid Channel
In this model, fluid is flowing through a channel containing a flexible obstacle. Due to the viscous and pressure forces asserted by the fluid, the obstacle bends.
With the obstacle undergoing a large deformation, the fluid flow domain also changes considerably. COMSOL Multiphysics takes these c...
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Electroosmotic Micromixer
Microlaboratories for biochemical applications often require rapid mixing of different fluid streams. At the microscale, flow is usually highly ordered laminar flow, and the lack of turbulence makes diffusion the primary mechanism for mixing.
While diffusional mixing of small molecules (and ther...
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Magnetic Drug Targeting
Current research on methods to target chemotherapy drugs in the human body includes the investigation of bio compatible magnetic nano-carrier systems, e.g., magnetic liquids such as ferrofluids. This model example investigates an external magnetic field and its interaction with blood flow containing...
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Nonisothermal Flow in a MEMS Heat Exchanger
This example concerns a stainless-steel MEMS heat exchanger, which you can find in lab-on-a-chip devices in biotechnology. Fluid flows through the tubes while a stainless steel heat sink/source surrounds the tubes.
The heat exchanger is modeled in 3D and accounts for heat transfer through both co...
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H-Micro Cell
This example was originally formulated by Albert Witarsa under Professor Bruce Finlayson’s supervision at the University of Washington in Seattle. It was part of a graduate course in which the assignment consisted of evaluating the potential of patents in the field of microfluidics through mathema...
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Drug Release from a Biomaterial Matrix
In this example, drug-release from a biomaterial matrix to damaged cell tissue is modelled.
Specifically, a nerve guide delivers a regenerating drug to damaged nerve ends. The model involves detailed drug release kinetics, with rate expressions handling drug dissociation/association reactions as...
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AC Electrokinetically Enhanced Surface Reactions
This model studies the use of AC electrokinetic forces to enhance the rate of transport of electrolytic reactants to a reaction surface on the wall of a microchannel.
If transport was to be governed by flow alone, then the flow velocity perpendicular to the surface would be so small that the ana...
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An Electrokinetic Valve in a Microchannel System
This model presents an example of pressure driven flow and electrophoresis in a microchannel system.
The modeled device is often used as an electrokinetic sample injector in biochips with well-defined sample volumes of dissociated acids and salts. The model presents a study of a pinched injection...
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Transport in an Electrokinetic Valve
This model presents an example of pressure driven flow and electrophoresis in a 3D micro channel system.
The model presents a study of a pinched injection cross valve during the focusing, injection, and separation stages.
Focusing is obtained through pressure driven flow of the sample and buff...
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DNA Degradation
In gene therapy, plasmid DNA (pDNA) can express desired proteins in the human body. A major issue in gene therapy consequently involves the transport of pDNA to target sites and the conversion between different forms of this species. Furthermore, the pDNA-forms interconvert and degrades with time....
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