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Here you will find presentations given at COMSOL Conferences around the globe. The presentations explore the innovative research and products designed by your peers using COMSOL Multiphysics. Research topics span a wide array of industries and application areas, including the electrical, mechanical, fluid, and chemical disciplines. Use the Quick Search to find presentations pertaining to your application area.

Electrical Response and Thermal Damage Assessment of Cutaneous and Subcutaneous Tissues to Noninvasive Radiofrequency Heating: A Computational Modeling Study

A. González-Suárez[1,2], J. N. Jimenez-Lozano[3], W. Franco[1]
[1]Wellman Center for Photomedicine, Massachusetts General Hospital & Harvard Medical School, Boston, MA, USA
[2]Biomedical Synergy, Electronic Engineering Department, Universitat Politècnica de València, Valencia, Spain
[3]ZELTIQ Aesthetics, Inc., Pleasanton, CA, USA

Electromagnetic radiofrequency (RF) sources are widely used to heat up cutaneous and subcutaneous tissues. The subcutaneous morphology of tissue consists of a fine, collagenous and fibrous septa network enveloping clusters of adipocyte cells; however, it is commonly regarded as a homogeneous fat layer in computational models. In the present study the objective is to assess the effect of the ...

Wireless Power and Communications for Implantable Biosensors

C. Romero[1], M. Mujeeb-U-Rahman[1]
[1]California Institute of Technology, Pasadena, CA, USA

Implantable biosensors have the potential to revolutionize the healthcare industry by allowing patients and their health care providers to continuously monitor blood pH levels, pCO2, proteins, metabolites, and a wide variety of other biomolecules. These devices need to operate completely wirelessly to be used for long term monitoring. Metal coils are attractive candidates for wireless power ...

Inlay Fixed Partial Denture Framework 3-D Structural Integrity Validation Using COMSOL Multiphysics®

T.M.R. Alho[1]

[1]Department of Electrical Engineering and Automation, University of Vaasa, Vaasa, Finland

Manual manufacturing of inlay fixed partial denture frameworks by metal casting can take hours of dental practitioners work time. This paper introduces 3-D simulations of premanufactured inlay fixed partial denture framework assembled from laser cut sheet metal parts. The study gives a good estimation of how well the frameworks can withstand strong human occlusion forces and masticatory cycle. ...

Dynamic Simulation of Bone Morphogenetic Protein Patterning in a 3D Finite-Element Model of the Danio Rerio Embryo

D. Umulis, and S. Lee
Purdue University
West Lafayette, IN

Zebrafish development of the dorsoventral axis relies on the spatiotemporal distribution of Bone Morphogenetic Protein (BMP) signaling, which is regulated by numerous secreted molecules such as Tolloid, Sizzled, and Chordin. The rich dorsal/ventral patterning network must achieve both spatial precision in the patterning of downstream targets and confernspatial precision at distinct time points ...

Particle Tracing: Analysis of Airborne Infection Risks in Operating Theatres

P. Apell[1], S. Hjalmarsson[1], T. Lindberg[1], I. Wernström[1], Y. Tarakonov[1], A. Erichsen Andersson[2], M. Karlsteen[1]
[1]Department of Applied Physics, Chalmers University of Technology, Göteborg, Sweden
[2]Sahlgrenska University Hospital, Department of Anesthesia, Surgery and Intensive Care, Göteborg, Sweden

Patients undergoing surgery are sensitive to infections. The operation staff may spread 10^4 particles per person per minute, of which ten percent are presumed bacteria-carrying. We visualize the influence of the personnel on the air and particle flows for the two most common ventilation systems in Swedish hospitals using Comsol Multiphysics with particle tracing.. The Laminar Air flow ...

Design of Microfluidic Device for Cellular Experiment Under Controlled Oxygen Tension

K. Funamoto[1], I.K. Zervantonakis[2], R.D. Kamm[2]
[1]Tohoku University, Sendai City, Miyagi, Japan
[2]Massachusetts Institute of Technology

Numerical simulation of oxygen tension was performed to develop a microfluidic device for three-dimensional real-time observation of cellular response under hypoxia. The optimal experimental condition was obtained through investigations of effects of parameters, such as device thickness and flow rates of media and gas, on oxygen tension.

Magnetic Fields and Materials for Medical Bone Reconstruction Assisted by Advanced Finite-Element Simulations

A. Sytcheva[1] and T. Herrmannsdörfer[1]
[1]Hochfeld-Magnetlabor Dresden, Forschungszentrum Dresden-Rossendorf, Dresden, Germany

We address the use of magnetic fields, forces, and materials for medical purposes. In particular, the treatment of osteochondral lesions is aimed for. To support ongoing activities in this field of research, last advances in using Finite Element Analysis (FEA) for the simulation of relevant processes, like magnetic targeting and magnetic fixation are reported. The availability of advanced ...

Numerical Validation of the Efficiency of Dual-Frequency Radiofrequency Ablation

A. Candeo[1] and F. Dughiero[1]
[1]Department Electrical Engineering, University of Padova, Padova, Italy

Radiofrequency Ablation (RFA) represents a valid alternative for treating liver metastases in medically complicated patients. Conventional devices currently operate at 500 kHz, due to good conducting properties of tissues. However, the use of lower frequencies (i.e. 20 kHz) has been recently reported to enhance the treatment effectiveness, due to a more pronounced difference in electrical ...

Photon Migration Through Multiple Layers of Biological Tissue

M.S. Yeoman[1], E. Sultan[2]
[1]Continuum Blue, Tredomen, Ystrad Mynach, United Kingdom
[2]College of Technological Studies, PAAET, Adailiyah, Kuwait

The modeling of light propagation through multiple layers of biological tissue are assessed & compared to the theoretical predictions by Perelman at al. [94 & 95] of the most-favorable-path (MFP). The MFP on which photons will be found can be obtained from the path of the net flux propagation using the diffusion equation. The diffusion equation is valid when studying diffuse light propagation, ...

Multiscale Electromagnetic Modeling of Contractions in the Pregnant Uterus - new

V. Tidwell[1], P. LaRosa[2], M. Zhang[1], H. Eswaran[3], A. Nehorai[1]
[1]Department of Electrical & Systems Engineering, Washington University in St. Louis, St. Louis, MO, USA
[2]Monsanto Company, Technology Pipeline Solutions, St. Louis, MO, USA
[3]OB/GYN Department, University of Arkansas for Medical Sciences, Little Rock, AR, USA

Uterine contractions during pregnancy are currently poorly understood – experts disagree on the mechanisms by which contractions propagate through the organ and the structural layout of the uterine muscle fibers. We have developed a multi-scale model of the uterus, at the cellular, tissue, and organ levels. By comparing simulated abdomen-level magnetic field readings from our model to clinical ...