L. Garber[1,2], G. S. B. Williams, W. J. Lederer
Fischell Department of Bioengineering, University of Maryland, Baltimore, MD, USA
Center for Biomedical Engineering & Technology, University of Maryland, Baltimore, MD, USA
This project involves a simplified biological problem that was used to test the potential of COMSOL Multiphysics® software for cardiac myocyte spatial modeling. We made several assumptions to simplify the biological complexity and to highlight the geometrical structures (i.e., lack of sarcoplasmic reticulum, lack of contractile apparatus). We explored the role of the t-tubular network on ...
H.H. Chen-Mayer, and R. Tosh
Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, Maryland, USA
Water calorimetry is employed to establish a primary reference standard for radiation dosimetry by measuring the temperature rises in a water phantom (a cube of about 30 cm x 30 cm x 30 cm) subjected to a beam of ionizing radiation. We use COMSOL Multiphysics to model the system using the Heat Transfer module and the Incompressible Navier-Stokes module with a geometry of 2D-axial ...
A.K. Dwivedi, R.M. Patrikar, R.B. Deshmukh, and G. Pendharkar
Visvesvaraya National Institute of Technology, Nagpur, Maharashtra, India
Testing and verification is very important to increase reliability of a system. In water analysis its purity is verified using different test methods. Biosensors are very useful to detect the microorganisms present in water. This paper presents a method to detect E.coli bacteria in water depending upon the capacitance modulation in the presence and absence of E.coli cell, which is simulated in ...
The Effect of Cartilaginous Rings on Deposition by Convection, Brownian Diffusion and Electrostatics
Luleå University of Technology, Luleå, Sweden
This paper presents a numerical study of the deposition of spherical charged nanoparticles caused by convection and Brownian diffusion in a pipe with a cartilaginous ring structure. The model is supposed to describe deposition of charged particles in the upper generations of the tracheobronchial tree of the human lung. The upper airways are characterized by a certain wall structure called ...
J. Anza, and M. Esteves
Department of applied mathematics, University of the Basque Country, Bilbao, Spain
University of the Basque Country, Bilbao, Spain
This work deals with the computer simulation of the blood flow, the arterial wall deformation and their 3D bidirectional interaction, including initial stresses and root displacements. The flow is laminar and steady with flexible walls modeled with a hyperelastic Demiray material model. Poiseuille formula is used to check the bidirectional interaction. 2D axisymmetric and full 3D models have ...
D. Iber, D. Menshykau, and P. Germann
Department of Biosystems Science and Engineering
Organogenesis is a tightly regulated process that has been studied experimentally for decades. Computational models can help to integrate available knowledge and to better understand the underlying regulatory logic. We are currently studying mechanistic models for the development of limbs, lungs, kidneys, and bone. We have tested a number of alternative methods to solve our spatio-temporal ...
E. Bianchi, M.F. Bello, I. Critelli, G. Dubini
Politecnico di Milano, LaBS, Laboratory of Biological Structure Mechanics, Milano, Italy
Swiss Federal Institute of Technology (EPFL), Laboratory of Life Sciences Electronics - Swiss Up Chair, Lausanne, Switzerland
A microfluidic thermal cycler for Polymerase Chain Reaction (PCR) has been modeled. A microliter sample is driven along the microchannel by a flow generated by means of electroosmotic micropumps, activated in sequence. Several multichannel pumps configurations have been separately modeled and the efficiency of each device has been evaluated with regard to the effective flowrate and the back ...
A Simplified Numerical Model for Simulating Sliding Door and Surgical Staff Movement in an Operating Theater
Dipartimento di Energetica, Università di Firenze, Firenze, Italy
This paper deals with a numerical investigation on sliding door and people moving effects on the indoor climate of a standard ISO5 class OT with an ultraclean air filter system and a total ceiling unidirectional diffuser. A simple method to analyze the effects on the OT climate by different sliding door conditions combined with crossing persons and persons with a stretcher crossing is provided. ...
P. Apell, S. Hjalmarsson, T. Lindberg, I. Wernström, Y. Tarakonov, A. Erichsen Andersson, M. Karlsteen
Department of Applied Physics, Chalmers University of Technology, Göteborg, Sweden
Sahlgrenska University Hospital, Department of Anesthesia, Surgery and Intensive Care, Göteborg, Sweden
Patients undergoing surgery are sensitive to infections. The operation staff may spread 10^4 particles per person per minute, of which ten percent are presumed bacteria-carrying. We visualize the influence of the personnel on the air and particle flows for the two most common ventilation systems in Swedish hospitals using Comsol Multiphysics with particle tracing.. The Laminar Air ...
P. Guha, P. Sharma, V. Malhotra, S. Mishra
CSIR - Central Scientific Instruments Organisation, Chandigarh, India
Proper storage of grains depends on minimizing attacks of insects, fungi, mites, etc. Development of such pests can be controlled by controlling the temperature of the storage chamber. Hence, before designing grain storage chambers, mathematical modeling and numerical simulations should be performed to predict the temperature distributions. Changes in storage temperature may occur due to several ...